Monoclonal antibodies reactive with tumor proliferating cells

Details Monoclonal antibodies reactive with tumor proliferating cells Monoclonal antibodies reactive with tumor proliferating cells

1994-11-07

1998-05-19

Loring, Susan A.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241741, 435344, 435 7021, 4351721, 5303888, 5303871, A61K 39395, C12N 510, C12N 512, C07K 1630

Patent

active

057532290

ABSTRACT:
This invention concerns monoclonal antibodies directed against breast carcinoma cells. Immunoglobulin secreting hybridoma cultures are produced by hybridoma technology using undifferentiated breast cancer cells as antigens for immunization. Hybridomas secreting antibodies highly reactive with tumor proliferating cells are selected. These monoclonal antibodies have particular application in aiding the diagnosis or treatment of cancer.

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