Monoclonal antibodies reactive with a human atheroma associated

Details Monoclonal antibodies reactive with a human atheroma associated Monoclonal antibodies reactive with a human atheroma associated

1990-10-17

1993-03-23

Chan, Y. Christina

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

530422, 530412, 4351722, 424 88, C12P 2108, C07K 318, C12N 1502, A61K 3900

Patent

active

051963248

ABSTRACT:
The present invention relates to a naturally occurring, minimally modified LDL antigen which is present in human atherosclerotic lesions as well as in the serum of a high percentage of patients with coronary artery disease. The invention also comprises antibodies reactive with the antigen, hybridoma cell lines that produce the antibodies of the inveniton, and methods for using the antibodies in the diagnosis and treatment of atherosclerotic disease.

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