Monoclonal antibodies reactive with a human atheroma associated

Details Monoclonal antibodies reactive with a human atheroma associated Monoclonal antibodies reactive with a human atheroma associated

1995-03-30

1997-01-28

Loring, Susan A.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

435 7021, 4351722, 435332, 530350, 5303871, 5303881, 53038825, 5303893, 530830, C12N 512, C12N 1502, C12P 2108, C07K 1618

Patent

active

055977260

ABSTRACT:
The present invention relates to a naturally occurring, minimally modified LDL antigen which is present in human atherosclerotic lesions as well as in the serum of a high percentage of patients with coronary artery disease. The invention also comprises antibodies reactive with the antigen, hybridoma cell lines that produce the antibodies of the invention, and methods for using the antibodies in the diagnosis and treatment of atherosclerotic disease.

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