Monoclonal antibodies immunoreactive with lipopolysaccharide bin

Details Monoclonal antibodies immunoreactive with lipopolysaccharide bin Monoclonal antibodies immunoreactive with lipopolysaccharide bin

1996-07-15

1998-05-19

Loring, Susan A.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

435326, 5303884, 5303871, 5303881, C12N 512, C07K 1612

Patent

active

057535043

ABSTRACT:
The present invention concerns a method of treating LBP-mediated LPS-induced myeloid cell activation comprising administering a therapeutically effective amount of an anti-LBP monoclonal antibody molecule. A therapeutic composition comprising anti-LBP antibody molecules in a pharmaceutically acceptable excipient is also contemplated.

REFERENCES:
Tobias, et al., "Isolation of a Lipopolysaccharide-Binding Acute Phase Reactant From Rabbit Serum", J. Exp. Med., 164: 777-793 (1986).
Tobias, et al., "Identification of a Lipid A Binding Site in the Acute Phase Reactant Lipopolysaccharide Binding Protein", J. Biol. Chem., 264: 10867-10871 (1989).
Wright, et al., "CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein", Science, 249: 1431-1433 (1990).
Schumann, et al., "Structure and Function of Lipopolysaccharide Binding Protein", Science, 249: 1429-1431 (1990).
Gallay, P. et al., Experientia, 48: A66, 1992.
Waldman, T.A., Science, 252: 1657-1662, 1991.
Pugin, J. et al., PNAS, 90(7):2744-2748, 1993 Apr.
Leturcq, D. et al., Cell Biochem, Suppl O (16 Part C), 161, Mar. 1-7, 1992.
Martin, T.B. et al., J. Clin Investigations, 90:2209-2219, Dec, 1992.
Tabias, P.S. et al., Am. J. Resp. Cell. Mol. Biol, 7:239-245, 1992.

Affiliated with

Also associated with

Rating

Monoclonal antibodies immunoreactive with lipopolysaccharide bin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibodies immunoreactive with lipopolysaccharide bin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibodies immunoreactive with lipopolysaccharide bin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1852261