Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1986-08-08
1990-06-19
Warden, Robert J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 7021, 4351722, 43524027, 435810, 436501, 436512, 436518, 436548, 436808, 424 851, 424 852, 530351, 530387, G01N 3353
Patent
active
049353438
ABSTRACT:
The present invention is concerned with novel monoclonal antibodies which bind to Interleukin-1.beta. and do not bind to Interleukin-1.beta.. The antibodies bind to Interleukin-1.beta. and block receptor binding and biological activity. The antibodies find use in, for example, diagnostic methods such as an assay for the detection of Interleukin-1.beta..
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Kock et al., "Characterization of a Monoclonal Antibody Directed Against the Biologically Active Site of Human Interleukin 1", J. Exp. Med., vol. 163, Feb. 1986, pp. 463-468.
Allison Anthony C.
Eugui Elsie M.
Kenney John S.
Masada Marvin P.
Leitereg Theodore J.
Nyari Linda J.
Spiegel Carol A.
Syntex (U.S.A.) Inc.
Warden Robert J.
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