Monoclonal antibodies for inducing tolerance

Details Monoclonal antibodies for inducing tolerance Monoclonal antibodies for inducing tolerance

1994-08-12

1997-11-25

Feisee, Lila

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241431, 4241531, 4241541, 4241731, 514 11, A61K 39395, A61K 3702

Patent

active

056909330

ABSTRACT:
Tolerance to an antigen is induced in a subject by administering a non-depleting CD4 monoclonal antibody and a non-depleting CD8 monoclonal antibody. Tolerance to the antigen can be induced under cover of these antibodies. A depleting CD4 monoclonal antibody and/or a depicting CD8 monoclonal antibody may be administered prior to the non-depleting antibodies.

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