Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1986-07-23
1988-04-12
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
435 68, 435 70, 4351722, 43524027, 424 11, 424 85, 436548, 530388, 514 2, C07K 1504, A61K 39395
Patent
active
047375795
ABSTRACT:
The present invention is concerned with novel monoclonal antibodies which define antigens associated with human non-small cell lung carcinomas ("NSCLC"). The antibodies bind to normal human cells to a lesser degree than to tumor cells. The antibodies find use in diagnostic methods such as the detection of malignant cells associated with NSCLC and in therapeutic methods.
REFERENCES:
patent: 4172124 (1979-10-01), Koprowski
Natali, P. G. et al, Cancer Research 42:583-589 (1982).
Moody, T. W. et al, Science, 214:1246-1248 (12-1981).
Cuittitta, F. et al, Proc. Natl. Acad. Sci, USA, 78(7): 4591-4595 (7-1981).
Minna, J. D. et al, In Vitro, 17(12):1058-1070 (12-1981).
Kennel, A. J. et al, Cancer Research, 41(9,PT1):3465-3470 (1981).
Sikora, K. et al, British J. Cancer, 43(5):696-700(1981).
Baylin, A. B. et al, Proc. Natl. Acad. Sci, USA, 79:4650-4654 (8-1982), see table 1.
Carney, D. N. et al, Pathobiology Annual, 12:115-136 (1982), see pp. 131-132.
Gazdar, A. F. et al, Seminars in Oncology, 10:3-19 (3-1983), see p. 14.
Hollinshead, A. C. et al, Cancer Detect. Prevent., 6:185-191 (1983).
Mulshine, J. L. et al, Journal of Immunology, 131(1):497-502 (1983).
Huang, L. C. et al, Arch. Bioch. Bioghys., 220(1):318-320 (1983).
Saji, S. et al, Hybridoma, 3(2):119-130 (1984), Biosis Abstract 79005569.
Bosslet, K. et al, Behring Inst. Mitt., 74:27-34 (1984), Chem. Abst. CA 101(9):70668B.
Varki, et al, Cancer Research, 44(2):681-687 (1984), Chem. Abst. CA 100(11):83935R.
Rosen, S. T. et al, Cancer Research, 44(5):2052-2061 (1984), Bios. Abstract 79014658.
Van Muyen, G. et al, Amer. J. Pathol., 116(3):363-369, Bio. Abst. 79023605.
Princler, G. S. et al, Cancer Research, 42:843-848 (3-1982).
Mazauric, T. et al, Cancer Research, 42:150-154 (1-1982).
Braatz. S. A. et al, Cancer Research, 42:849-855 (3-1982).
Sokol, R. E. et al, Federat. Proceed., 41(3):409, abstract 816 (4-1982).
Brown Joseph P.
Hellstrom Ingegerd
Hellstrom Karl E.
Horn Diane
Linsley Peter
Moskowitz Margaret
Oncogen
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