Monoclonal antibodies for DNA-RNA hybrid complexes and their use

Details Monoclonal antibodies for DNA-RNA hybrid complexes and their use Monoclonal antibodies for DNA-RNA hybrid complexes and their use

1988-02-12

1989-09-12

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 6, 435 7, 4351722, 530387, 424 858, 935104, C12Q 168, G01N 33577, A61K 39395

Patent

active

048659800

ABSTRACT:
Monoclonal antibodies are provided capable of distinguishing DNA-RNA hybrid complexes from single stranded DNA and RNA and double stranded DNA and RNA. The antibodies find particular use in determining the presence of a specific nucleic acid sequence on a solid surface. Single stranded polynucleotide is fixed to a solid (gel) surface and then hybridized with the complementary probe. The hybrid complex specific monoclonal antibody is then added to bind to any hybrid complexes which have formed. By appropriate label, the hybrid complex may be visualized in a variety of ways.

REFERENCES:
patent: 4732847 (1988-03-01), Stuart et al.

Affiliated with

Also associated with

Rating

Monoclonal antibodies for DNA-RNA hybrid complexes and their use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibodies for DNA-RNA hybrid complexes and their use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibodies for DNA-RNA hybrid complexes and their use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-915889