Monoclonal antibodies and their use in a method for monitoring s

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 34, 435948, 435960, 435973, 435110, 436525, 436548, G01N 33577

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050859854

ABSTRACT:
Monoclonal antibodies which recognize activated T lymphocytes are secreted by hybridomas produced by conventinal fusion and selection methodology following immunization of mice with a human lymphocyte fraction containing T lymphocytes activated by a mitrogen or an antigen. The monoclonal antibodies are used in a method to monitor subsets of activated T lymphocytes present, for example, from a patient's blood.

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