Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1990-12-07
1992-11-24
Doll, John J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 7021, 4351722, 43524027, 5303881, 53038835, 5303894, 530864, 530868, 424 858, 424 86, G01N 33569, C12N 520, C07K 1528, A61K 3942
Patent
active
051660504
ABSTRACT:
Methods and composition for HIV diagnosis and treatment using monoclonal antibodies reactive with one or more neutralizing regions of HIV proteins, using the peptides or homologs thereof from that region, and using related nucleic acid segments. Exemplary neutralizing regions include selected portions of the env and gag genes from various HIV isolates. Monoclonal antibody secreting cell lines include HIV-gp110-1, -2, -3, -4, -5 and -6 (A.T.C.C. Accession Nos. HB9175, HB9176, HB9177, HV9405, HB9406 and HB9404, respectively) and HIV-p25-2, -3, -6 and -7 (A.T.C.C. Accession Nos. HB9407, HB9408, HB9409 and HB9410, respectively).
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Cosand Wesley L.
Dickinson Edna S.
Gosting Larry H.
McClure Janela
Shriver Mary K.
Bristol--Myers Squibb Company
Budens Robert D.
Doll John J.
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