Monoclonal antibodies and antisera to intragonadal regulatory pr

Details Monoclonal antibodies and antisera to intragonadal regulatory pr Monoclonal antibodies and antisera to intragonadal regulatory pr

1987-03-26

1990-03-27

Moskowitz, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530350, 530351, 530853, 530808, 43524027, 424 858, A61K 39395, C07K 1514, C07K 1516

Patent

active

049122010

ABSTRACT:
A protein having a molecular weight of from about 10,000 to 18,000 daltons, isoelectric points of from about pH 4.0 to 6.5 and having the reversible biological effect of inhibiting aromatase activity in a biological system, and antibodies to the protein, modulate follicular development and spermatogenesis and provide for diagnostic tests of gonadal functions.

REFERENCES:
DiZerega et al, J. Clin Endocrin Metab, 54(6), 1091-1096, (1982).
DiZerega et al., J Clin Endocrin Metab, 56(1), 35-41 and 147-155 (1983).
Battin et al, J Clin Endocrin Metab., 60(6), 1116-1119, (1985).

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