Monoclonal antibodies against β 3 integrins

Details Monoclonal antibodies against β 3 integrins Monoclonal antibodies against β 3 integrins

2008-04-11

2010-06-08

Gambel, Phillip (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S130100, C424S141100, C424S143100, C424S144100, C424S173100, C435S007100, C435S334000, C435S343000, C435S346000, C530S387100, C530S388100, C530S388220, C530S388700

Reexamination Certificate

active

07731966

ABSTRACT:
Monoclonal antibodies prepared against platelet β3integrin useful in antithrombotic therapy or in models of thrombosis, thrombocytopenia, and anti-angiogenesis. The antibodies are prepared using β3integrin deficient (β3−/−) mice immunized against platelets or β3integrin fragments.

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