Monoclonal antibodies against the epitope YPYDVPDYA, a...

Details Monoclonal antibodies against the epitope YPYDVPDYA, a... Monoclonal antibodies against the epitope YPYDVPDYA, a...

2007-08-14

2007-08-14

Zeman, Robert A. (Department: 1645)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds antigen or epitope whose amino acid sequence is...

C424S093200, C424S141100, C424S186100, C424S206100, C435S346000

Reexamination Certificate

active

09284787

ABSTRACT:
The invention concerns monoclonal antibodies against the epitope YPYDVPDYA (SEQ ID NO: 1) which is derived from the haemagglutinin of the human influenza virus and are suitable for the detection and isolation of native haemagglutinin of the human influenza virus, of modified haemagglutinin or of haemagglutinin fusion proteins and have an affinity of >108M−1, in particular of 109to 1010M−1.

REFERENCES:
patent: WO 92/09300 (1992-06-01), None
Kuby (Immunology, Second Edition, W.H. Freeman and Company, 1994, pp. 160-164).
Greenspan et al. (Nature Biotechnology 7: 936-937, 1999).
Chen, et al., “Expression and localiztion of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag,” Proc. Natl. Acad. Sci, USA, 90:6508-6512 (1993).
Field, et al., “Purification of a RAS-Responsive Adenylyl Cylase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method,” Molecular and Cellular Biology, 8:2159-2165 (1988).
Green, et al., “Immunogenic Structure on the Influenza Virus Hemagglutinin,” Cell, 28:477-487 (1982).
Hinds, et al., “Synthesis, Conformational Properties, and Antibody Recognition of Peptides Containing Beta-Turn Mimetics Based on Alpha-Alkyproline Dervatives,” Journal of Medicinal Chemistry,.34:1777-1789 (1991).
Kolodziej, et al., “Epitope Tagging and Protein Surveillance,” Biochemistry of Gene Expression, 194:508-519 (1991).
Wilson, et al., “The Structure of an Antigenic Determinant in a Protein,” Cell, 37:767-778 (1984).
“Generation of Protein-Reactive Antibodies by Shon Peptides Is An Event of High Frequency: Implications for the Structural Basis of Immune Recognition,” Niman et al., Proc. Natl. Acad. Sci., USA, vol. 80, Aug. 1983, pp. 4949-4953.

Affiliated with

Also associated with

Rating

Monoclonal antibodies against the epitope YPYDVPDYA, a... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibodies against the epitope YPYDVPDYA, a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibodies against the epitope YPYDVPDYA, a... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3898745