Monoclonal antibodies against leukocyte adhesion receptor .beta.

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

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4241331, 4241441, 4241721, 4241831, 435 7021, 4351723, 435325, 435334, 5303882, 5303917, A61K 39395, A61K 3940, C12P 2104, C07K 1600

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058885080

ABSTRACT:
Monoclonal antibodies and method for ameliorating an immune response disorder. The monoclonal antibodies are specific for an epitope present on the leukocyte adhesion receptor .beta.-chain.

REFERENCES:
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McMichael Leucocyte Typing III White Cell Differentiation Antigens Oxford University Press, 1987 See Preface.
Ward et al. Therapeutic Immunology vol. 1:165-171, 1994.
Fahey et al., Clin. exp.Immunol. 88:1-5, 1992.
Vedder et al., J. Clin. Invest. 81:939-44, 1988.
Harris et al. Tibtech 11:42-44, 1993.
Pastan et al. Cell 47:641-648, 1986.
James E. Hildreth and Jennifer A. Hyman, Production and Characterization of Monoclonal Anti-CD8 Anti-Idiotype Antibodies; Molecular Immunology, 26(12) :1155-1167, 1989.
James E. Hildreth and J. Thomas August, The Human Lymphocyte Function-Associated (HLFA) Antigen and a Related Macrophage Differentiation . . . ; The Journal of Immunology, 134(5) :3272-3280, 1985 .

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