Monoclonal antibodies against human Tumor Necrosis Factor .alpha

Details Monoclonal antibodies against human Tumor Necrosis Factor .alpha Monoclonal antibodies against human Tumor Necrosis Factor .alpha

1991-12-13

1995-07-25

Lacey, David L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

53038824, 5303871, 53038823, 4247331, 4241581, A61K 39395, C12N 520, C12N 512, C07K 1528

Patent

active

054361540

ABSTRACT:
A monoclonal antibody is provided which is able to neutralize both human TNF .alpha. and TNF .beta., or a binding fragment thereof. A stable hybridoma cell line and progeny thereof are also provided which secrete such a monoclonal antibody. The monoclonal antibody or a fragment thereof may be used to detect the content of human TNF in a sample of body fluid.

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