Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reissue Patent
2007-08-07
2007-08-07
Huff, Sheela J. (Department: 1643)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007200, C435S040510, C435S040520, C435S325000, C435S328000, C435S329000, C435S330000, C435S332000, C435S344000, C530S388800, C530S387100, C530S387300, C530S387500, C530S387700, C530S388100, C530S391100, C530S391300, C530S391700
Reissue Patent
active
09633034
ABSTRACT:
Monoclonal antibodies, in particular 33.28 and 31.1, and chimeric antibodies, in particular mouse/humans chimeric Chi #1 specific for glycoprotein antigens of colon carcinoma-associated antigens which are immunogenic in humans, are disclosed. Such antibodies, and fragments and derivatives thereof, are useful in immunodiagnosis and immunotherapy of human colon, breast, and ovarian cancer, and for purification of antigens which can serve as immunotherapeutic agents. Methods of detecting the colon carcinoma-associated antigen in a sample, and methods for treating subjects having colon, breast, and ovarian carcinomas are disclosed.
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Arlen Myron
Tsang Kwong Y.
Baker & Botts LLP
Huff Sheela J.
International Bio-Immune Systems Inc.
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