Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-01-03
2006-01-03
Siew, Jeffrey (Department: 1642)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387100
Reexamination Certificate
active
06982322
ABSTRACT:
An anti-NAIP monoclonal antibody recognizing a human apoptosis inhibitory protein NAIP having the amino acid sequence of SEQ ID NO: 1, which is produced from hybridoma prepared by fusing a myeloma cell line with antibody-producing cell of mammal immunized by antigen containing a polypeptide which comprises amino acid sequence of the 256–586th, the 841–1052nd or parts thereof in SEQ ID NO: 1, NAIP assay method using the antibody, and NAIP assay kits.
REFERENCES:
patent: 6511828 (2003-01-01), Thompson et al.
patent: 97/26331 (1997-07-01), None
Harlow et al (1988, Antibodies A Laboratory Manual, Cold Spring Harbor Laboratory, pp. 556, 588, 579-81 only).
Roy et al (Dec. 1, 1997, EMBO J., vol. 16, pp. 6914-25).
Biological Abstracts, No. 199799598887, D. G. Xu et al., “Distribution of Neuronal Apoptosis Inhibitory Protein-Like Immunoreactivity in the Rat Central Nervous System”, & Journal of Comparative Neurology, 1997, vol. 382, No. 2, pp. 247-259.
Natalle Roy et al., “The Gene for Neuronal Apoptosis Inhibitory Protein is Partially Deleted in Individuals with Spinal Muscular Atrophy”, Cell, 1995, vol. 80, No. 1, pp. 167-178.
Ikeda Johe
Sakai Harumi
Japan Sciences and Technology Corporation
Siew Jeffrey
Toyo Boseki Kabushiki Kaisya
Wenderoth , Lind & Ponack, L.L.P.
Yu Misook
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