Monoclonal antibodies against chicken T-lymphocytes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 7021, 4351722, 43524027, 53038875, C07K 300, C17Q 100, C17N 1500, A01K 3514

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active

054496101

ABSTRACT:
Seven murine hybridoma cell lines capable of secreting monoclonal antibodies that can identify subpopulations of chicken lymphocytes have been developed. Precursor cytotoxic and suppressor T lymphocytes, precursor helper lymphocytes, and mature T lymphocytes may be distinguished by use of these antibodies.

REFERENCES:
Hyun S. Lillihoj, "Production and Flow Cytometric Analysis of Monoclonal Antibodies Reactive with Subpopulations of Chicken Lymphocytes," In Avian Immunology, pp. 87-97, Alan R. Liss, Inc. (1987).
Marion M. Chan et al., "Identification of the Avian Homologues of Mammalian CD4 and CD8 Antigens," J. Immunol. 140: 2133-2138 (1988).
Elizabeth Houssaint et al., "Tissue Distribution and Ontogenic Appearance of a Chicken T Lymphocyte Differentiation Marker," Eur. J. Immunol. 15: 305-308 (1985).
K. Hala et al., "3. A Monoclonal Antibody Reacting with a Membrane Determinant Associated with T Cell Activation in the Chicken," J. Immunobiol. 168: 2 (1985) (Abstract).
Chen-lo H. Chen et al., "Chicken Thymocyte-Specific Antigen Identified by Monoclonal Antibodies: Ontogeny, Tissue Distribution, and Biochemical Characterization," Eur. J. Immunol. 14: 385-391 (1984).
J. Richard Pink et al. "Monoclonal Antibodies Against Chicken Lymphocyte Surface Antigens," Hybridoma 2: 287-296 (1983).
Vernon T. Oi et al., "Immunoglobulin-Producing Hybrid Cell Lines," In Selected Methods in Cellular Immunlogy, B. B. Mishell and S. M. Shiigi (eds.), pp. 351-372 (1980).

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