Monoclonal anti-ornithine decarboxylase antibody and method of p

Details Monoclonal anti-ornithine decarboxylase antibody and method of p Monoclonal anti-ornithine decarboxylase antibody and method of p

1983-10-11

1987-01-20

Warren, Charles F.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 68, 435 70, 4351722, 435241, 435948, 530387, 935104, C12N 500, C07K 1504

Patent

active

046379843

ABSTRACT:
Monoclonal anti-ornithine decarboxylase antibody is produced by cell hybrids between hypoxanithine phosphoriboxyltransferase deficient myeloma cells and spleen cells derived from an animal previously immunized with ornithine decarboxylase. By means of immunoaffinity chromatography using cyanogen bromide-activated agarose coupled with the antibody, ornithine decarboxylase in animal cell extracts can be highly purified in high yield.

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