Monoclonal anti-idiotype antibodies

Drug – bio-affecting and body treating compositions – Lymphokine

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530387, 43524027, 435 7, 424 86, 436548, A61K 39395

Patent

active

048162493

ABSTRACT:
Monoclonal anti-idiotype antibodies against cell surface Ig of human B-cell tumors, labeled conjugates of such antibodies, immunotherapeutic compositions containing such antibodies, and a process for making such antibodies. The nodular lymphoma of a patient treated with a monoclonal anti-idiotype antibody against the cell surface IgM of the patient's tumor went into complete remission.

REFERENCES:
patent: 4172124 (1979-10-01), Koprowski
patent: 4513088 (1985-04-01), Levy et al.
Hamblin et al, Chem Abs, 94(11):76974g, 1980.
Krolick et al, Imm Rev, 48, 81-106, 1979.
Haughten et al, J. Immunol., 121(6), Dec. 1978.
Sevier et al, Clin. Chem., 27(11), 1797-1806, 1981.
Kohler et al., (1975), Nature, 256: 495-497.
Levy et al., in Monoclonal Antibodies, (Kennet et al., eds. Plenum Press, 1980), pp. 137-153.
Brown et al., (1980), J. Immunol., 125:1037-1043.
Littlefield, (1964), Science, 145:709-710.
Stevenson et al., (1977), Fed. Proc., 36:2268-2271.
Stevenson et al., (1975), Nature, 254:714-716.
Hough et al., (1976), J. Exp. Med., 144:960-969.
Levy et al., (1978), Proc. Natl. Acad. Sci. (USA), 75(5):2411-2415.
Kennet et al., in Methods in Enzymology (Academic Press, N.Y. 1979), pp. 345-359.
Mayumi et al., (1982), J Immunol., 129(2):904-910.
Hamblin et al., (1980), Br. J. Cancer, 42:495-502.
Hatzubai et al., (1981), J. Immunol., 126(6):2397-2402.
Thorpe et al., (1978), Nature, 271:752-755.
Gerhard et al., (1981), Proc. Natl. Acad. Sci., 78(5):3225-3229.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Monoclonal anti-idiotype antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal anti-idiotype antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal anti-idiotype antibodies will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1658050

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.