Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1983-12-02
1987-04-28
Marantz, Sidney
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530388, 530308, 436548, 435 68, 4351722, 435240, 435241, 435 43, 435 948, 424 85, C07K 300, C07K 1500, C12N 1500, G01N 3353
Patent
active
046615865
ABSTRACT:
Monoclonal anti-idiotype antibodies against cell surface Ig of human B-cell tumors, labeled conjugates of such antibodies, immunotherapeutic compositions containing such antibodies, and a process for making such antibodies. The nodular lymphoma of a patient treated with a monoclonal anti-idiotpye antibody against the cell surface IgM of the patient's tumor went into complete remission.
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Kohler, G. and Milstein C., Nature, vol. 256, 495-497, (1975).
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Hamblen, T. J., et al., Br. J. Cancer, vol. 42, 495-501, (1980).
Hough, D. W. et al., J of Exp. Med., vol. 144, 960-966, (1976).
Levy R. et al., Monoclonal Antibodies, Plenum Press, Ed by Kennet, et al., 1980,137-157.
Brown, S. et al., J. Immunology, vol. 125, No. 3, 1037-1043, (1980).
Hatzuboi et al., Journal of Immunology, vol. 126, No. 6, pp. 2397-2402, Jun. 1981.
Dilley Jeanette
Levy Ronald
Maloney David G.
Miller Richard A.
DeSantis Patricia L.
Marantz Sidney
The Board of Trustees of the Leland Stanford Junior University
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