Monobactam hydrazides containing catechol sulfonic acid groups

Details Monobactam hydrazides containing catechol sulfonic acid groups Monobactam hydrazides containing catechol sulfonic acid groups

1991-02-07

1991-12-31

Mars, Howard T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfonic acids or salts thereof

544224, 540553, 548356, 548951, C71, C07D24302, C07D23104, C07D22900, C07D23702, A61K 31095, A61K 31415, A61K 3150

Patent

active

050774328

ABSTRACT:
Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.3 and R.sub.4 are the same or different and each is hydrogen or alkyl or R.sub.3 and R.sub.4 taken together with the nitrogen atoms to which they are attached form a 1,2-diazacyclobutane, 1,2-diazacyclopentane, 1,2-diazacyclohexane, or 1,2-diazacycloheptane ring and Y, and Y.sub.2 are either hydrogen or hydroxy but are not the same; are useful chemical intermediates for the preparation of .beta.-lactam antibiotics.

REFERENCES:
patent: 3567769 (1971-03-01), Girard et al.
patent: 4775670 (1988-10-01), Sykes et al.

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