Monobactam hydrazides containing catechol sulfonic acid groups

Details Monobactam hydrazides containing catechol sulfonic acid groups Monobactam hydrazides containing catechol sulfonic acid groups

1990-01-22

1991-07-09

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540553, 544224, 548356, 548951, 548195, 562 52, A61K 31425, C07D41712, C07D41714, C07D27740

Patent

active

050307240

ABSTRACT:
Antibacterial activity is exhibited by novel compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof. R.sub.3 and R.sub.4 are the same or different and each is hydrogen or alkyl or R.sub.3 and R.sub.4 taken together with the nitrogen atoms to which they are attached form a 1,2-diazacyclobutane, 1,2-diazacyclopentane, 1,2-diazacyclohexane, or 1,2-diazacycloheptane ring.
Y.sub.1 and Y.sub.2 are either hydrogen or OR.sub.11 but are not the same.
R.sub.11 is hydrogen, alkanoyl of from one to ten carbon atoms, substituted alkanoyl of from two to ten carbon atoms, phenylcarbonyl, (substituted phenyl) carbonyl, heteroarylcarbonyl, phenylalkanoyl, (substituted phenyl) alkanoyl, or heteroarylalkanoyl.

REFERENCES:
patent: 4775670 (1988-10-01), Sykes et al.

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