Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2008-04-29
2008-04-29
Eyer, Yvonne (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C514S169000, C552S511000
Reexamination Certificate
active
07365221
ABSTRACT:
Betulin and dihydrobetulin acyl derivatives according to the present invention have been found to have potent anti-HIV activity. The compounds of the present invention have Formula I as described herein, or pharmaceutically acceptable salts thereof; wherein R1is a C2-C20substituted or unsubstituted carboxyacyl or ester thereof; R2is hydrogen, halogen, hydroxyl or —OR3, R3is C2-C20substituted or unsubstituted carboxyacyl; and R4is hydrogen or C(C6H5)3; wherein the dashed line represents an optional double bond between C20 and C29.
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Allaway Graham P.
Kashiwada Yoshiki
Lee Kuo-Hsiung
Wild Carl T.
Eyer Yvonne
Katakam Sudhakar
Niigata University of Pharmacy and Applied Life Sciences
Panacos Pharmaceuticals, Inc.
Sterne Kessler Goldstein & Fox P.L.L.C.
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