Monoacetals of hydroquinone

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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549416, 549475, C07C 43307

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active

058115935

ABSTRACT:
The present invention is for a process for preparing monoacetals of hydroquinone wherein said process provides for higher yields of greater purity. Said process utilizes a two step reaction wherein a protected hydroquinone is reacted with an enol ether to form a protected intermediate. Upon hydrogenolysis of said intermediate a final product, monoacetal hydroquinone, is formed having higher degree of purity and in greater yields that the yields attributed to reactions known in the art.

REFERENCES:
patent: 5585525 (1996-12-01), Carter et al.
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Bieg and Szeja, "Removal of O-Benzyl Protective Groups by Catalytic Transfer Hydrogenation", Communications, Jan. 1985.
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Banik et al. "Microwave-Induced organic Reaction Enhancement Chemistry. 4 Convenient synthesis of Anantiopure .alpha.-Hydroxy-.beta.-Lactams", Tetrahedron Letters, vol. 33, No. 25, pp. 3603-3606 (1992).
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Hanessian et al., "Facile Cleavage of Benzyl Ethers by Catalytic Transfer Hydrogenation", Synthesis, No. 5, pp. 396-397, May 1981.

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