Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-11-13
1976-11-09
Rush, Raymond V.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260240R, 260240A, 260240D, 2602401, 2602471L, 2602471M, 2602472A, 2602475E, 260268C, 26029362, 2602948R, 2602948G, 2602949, 260295K, 260295AM, 260307F, 2603323R, 2603477, 260564G, 260296R, 424248, 424250, 424263, 424267, 424272, C07D27106
Patent
active
039910679
ABSTRACT:
1,2,4-Oxadiazoles having as 3- and 5-substituents a hydrogen atom, an aliphatic, cycloaliphatic, araliphatic, aryl or heterocyclic group, or a carbamoyl group of the formula -- CONR.sup.1 R.sup.2 where R.sup.1 & R.sup.2 which can be the same or different, are hydrogen atoms or aliphatic, cycloaliphatic, araliphatic or aryl groups or, taken with the N atom, a heterocvolic ring; provided that at least one of the 3- or 5-substituents is an N-substituted carbamoyl group. Antimicrobial activity, and particularly antiviral, antiparasitic and antibacterial activity is shown in this group. The corresponding oxadiazolins are also described and are useful intermediates in the preparation of the oxadiazoles.
REFERENCES:
patent: 3478049 (1969-11-01), Von Esch et al.
patent: 3720668 (1973-03-01), Breuer
Ruccia et al.--C.A. 69, 77174s (1968).
Strani et al.--Gazz. Chim. Ital. 93, 482-484 (1963).
Gregory Gordon Ian
Seale Peter William
Warburton William Kingston
Glaxo Laboratories Limited
Rush Raymond V.
LandOfFree
Mono- or disubstituted 1,2,4,oxadiazoles which are substituted b does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mono- or disubstituted 1,2,4,oxadiazoles which are substituted b, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mono- or disubstituted 1,2,4,oxadiazoles which are substituted b will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1725044