Mono- and dialkylated prostynoic acid derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603459, 2604109R, 260413, 260448A, 260468D, 260471R, 260475R, 260488R, 260632Y, 424305, 424317, C07C 6138, C07C 6174

Patent

active

039324966

ABSTRACT:
Novel mono- and dialkylated prostynoic acid derivatives, prepared by condensation of a suitably substituted cyclopentene carboxylic acid or ester with a suitable organometallic alkynyl derivative, display valuable pharmacological properties. For example, they are potent inhibitors of gastric secretion.

REFERENCES:
patent: 3787449 (1974-01-01), Collins et al.
Pappo et al., Annals of N.Y. Academy of Sciences, Vol. 180, (1971).
Robert, Research in Prostaglandins, 2, No. 4, (1973).

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