Monkey and canine melanin concentrating hormone receptors

Details Monkey and canine melanin concentrating hormone receptors Monkey and canine melanin concentrating hormone receptors

2006-11-28

2006-11-28

Ulm, John (Department: 1649)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S007210, C435S252300, C435S320100, C530S350000, C536S023400

Reexamination Certificate

active

07141391

ABSTRACT:
Isolated polynucleotides encoding monkey and canine Melanin Concentrating Hormone (MCH) Type 2 receptors and chimeric polypeptides are provided. Vectors and cells for recombinant expression of such MCH receptor polypeptides, and isolated MCH receptor polypeptides are also provided. MCH receptor polynucleotides and polypeptides may be used, for example, to identify agents that specifically interact with MCH receptor. Such agents find use within therapies for humans and animals afflicted with conditions associated with MCH receptor activation.

REFERENCES:
patent: 6593108 (2003-07-01), Liu et al.
patent: WO 00/49046 (2000-08-01), None
patent: WO 00/75166 (2000-12-01), None
patent: WO 01/05947 (2001-01-01), None
patent: WO 01/07606 (2001-02-01), None
patent: WO 01/36479 (2001-05-01), None
patent: WO 01/68706 (2001-09-01), None
patent: WO 01/70975 (2001-09-01), None
patent: WO 02/03070 (2002-01-01), None
patent: WO 02/08290 (2002-01-01), None
patent: WO 02/36076 (2002-05-01), None
patent: WO 02/097394 (2002-12-01), None
Buggy et al. “Glucagon-Glucagon-like Peptide I Receptor Chimeras Reveal Domains That Determine Specificity of Glucagon Binding”, Mar. 1995, J. Biol. Chem. 270(13):7474-7478.
Holtmann et al. “Critical Contributions of Amino-terminal Extracellular Domains in Agonist Binding and Activation of Secretin and Vasoactive Intesinal Polypeptide Receptors”, Jun. 16, 1995, J. Biol. Chem. 270(24):14394-14398.
Kim et al. “Random Chimeragenesis of G protein-coupled Receptors”, Nov. 18, 1994, J. Biol. Chem. 269(46):28724-28731.
Meng et al. “Mapping the Receptor Domains Critical for the Binding Selectivity of delta-opioid Receptor Ligands”, 1996, Euro. J. Pharmacol. 311:285-292.
Schioth et al., “Chimeric Melatonin MC1 and MC3 Receptors: Identification of domains Participating in Binding of Melanocyte-Stimulating Hormone Peptides”, 1998, Mol. Pharmacol. 54:154-161.
Takagi et al. “Structural Basis of G Protein Specificity of Human Endothelial Receptors”, Aug. 28, 1995, J. Biol. Chem. 270(17):10072-10078.
Gether et al. “Chimeric NK1 (Substance P)/NK3(Neuromedin B) Receptors”, Apr. 15, 1993, J. Biol. Chem. 268(11):7893-7898.
Wu et al. “First Intracellular Loop of the Human Cholecystokinin-A Receptor Is Essential for Cyclic AMP Signalling in Transfected HEK-293 Cells”, Apr. 4, 1997, J. Biol. Chem. 272(14):9037-9042.
Rodriguez et al., “Cloning and Molecular Characterization of the Novel Human Melanin-Concentrating Hormone Receptor MCH2,” Mol. Pharmacol. (2001) 60:632-639.
An et al., “Identification and characterization of a melanin concentrating hormone receptor,” Proc. Natl. Acad. Sci. USA (2001) 98:7576-7581.
Sailer et al., “Identification and characterization of a second melanin concentrating hormone receptor, MCH-2R,” Proc. Natl. Acad. Sci. USA (2001) 98:7564-7569.
Mori et al., “Cloning of a Novel G Protein-Coupled Receptor, SLT, a Subtype of the Melanin-Concentrating Hormone Receptor,” Biochem. Biophys. Res. Comm. (2001) 283:1013-1018.
Hill et al., “Molecular Cloning and Functional Characterization of MCH2, a Novel Human MCH Receptor,” J. Biol. Chem. (2001) 276:20125-20129.
Chambers et al., “Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1,” Nature (1999) 400:261-265.
Saito et al., “Molecular characterization of the melanin-concentrating-hormone receptor,” Nature (1999) 400:265-269.
Lakaye et al., “Cloning of the rat brain cDNA encoding for the SLC-1 G protein-coupled receptor reveals the presence of an intron in the gene,” Biochimica et Biophysica Acta (1998) 1401:215-220.
Kolakowski et al., “Characterization of a human gene related to genes encoding somatostatin receptors,” FEBS Letters (1996) 398:253-258.

Affiliated with

Also associated with

Rating

Monkey and canine melanin concentrating hormone receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monkey and canine melanin concentrating hormone receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monkey and canine melanin concentrating hormone receptors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3671230