Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1981-02-18
1987-09-15
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 29, 436501, 436512, 436513, 436519, 436821, G01N 33533, G01N 33534, G01N 33554
Patent
active
046939679
ABSTRACT:
A diagnostic method and reagents for monitoring the efficacy of therapeutic treatment using the phenomenon of capping of cell membrane receptors, and is useful for relating receptor capping to clinical responses to therapy in patients with diseases, disorders, or malignancies involving cells that possess receptors. Therapeutic efficacy is determined by detecting receptors for activated substances, e.g., the third component of complement (C3), on cells having receptors therefor on the cell membrane surface, e.g., human lymphocytes, by the binding of an activated receptor substance, preferably labeled with a fluorescent or radioactive marker.
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Kepplinger Esther M.
Research Corporation
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