Monitoring particle aggregation by the use of a meniscus

Details Monitoring particle aggregation by the use of a meniscus Monitoring particle aggregation by the use of a meniscus

1991-03-18

1993-07-13

Nucker, Christine M.

Chemistry: analytical and immunological testing

Involving kinetic measurement of antigen-antibody reaction

436503, 436514, 436519, 436536, 436538, 436539, 436501, 435 71, 435 72, 435 725, 435296, 435315, G01N 33567, G01N 33558, G01N 33554, G01N 33536, G01N 33537, G01N 33539, G01N, G01N 33557, C12Q 100, C12M 124, C12M 106

Patent

active

052273121

ABSTRACT:
A method of monitoring the aggregation of cells in, for example, an immuno-agglutination assay, comprises promoting agglutination sonically in a capillary and inverting the capillary to cause agglutinated particles to settle at a meniscus. The granular appearance of agglutinated cells can be distinguished visually from the smooth distribution of non-aggregated cells.

REFERENCES:
Grundy et al. (1989) J. Clin Lab Immunol 30:93-96.

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