Monitoring one or more solutes in a biological system using opti

Details Monitoring one or more solutes in a biological system using opti Monitoring one or more solutes in a biological system using opti

1994-12-02

1998-07-21

Bahr, Jennifer

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

600473, 600476, A61B 500

Patent

active

057827559

ABSTRACT:
A scheme for monitoring one or more solutes in a biological system comprising the steps of: delivering light into a biological system containing one or more solutes, the light having a wavelength selected to be in a range wherein at least one of the one or more solutes is substantially non-absorbing; detecting at least first and second portions of the delivered light, the first portion having traveled through the biological system along one or more paths characterized by a first average path length, and the second portion having traveled through the biological system along one or more paths characterized by a second average path length that is greater than the first average path length; and comparing the first and second portions of the delivered light to monitor a concentration of one or more of the solutes in the biological system. Also described are schemes for monitoring low molecular weight polyhydroxy solutes, generally sugars (mannitol, fructose, sucrose, glucose), alcohols (methanol and propanediol), and electrolytes (sodium and potassium chloride).

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