Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-12-20
1997-01-14
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
5303888, 435810, 435975, 436 64, 436813, G01N 33574, G01N 3353, C07K 1600, C12P 2108
Patent
active
055938477
ABSTRACT:
A method for aiding in the diagnosis of, and monitoring the progression of, breast cancer in a patient by measuring the amount of NCA 50/90 in a blood sample, e.g. serum sample, obtained from the patient. Measurement in a single sample of an amount of NCA 50/90 significantly higher than the mean amount of NCA 50/90 in the normal population is an indication of breast cancer in the patient. The progression of breast cancer can also be monitored by performing a series of specific immunoassays over time to determine changes in the level of NCA 50/90 in blood samples. Increases in blood NCA 50/90 levels over time are indicative of a deteriorating condition whereas decreasing levels of blood NCA 50/90 over time indicate an improving condition.
REFERENCES:
Chavenel et al, Oncodev. Biol. and Med. 4:209-217 (1983).
Yeung et al, Tumor Biol. 9:119 (1992).
von Kleist et al, Br. J. Cancer 35:875-880 (1977).
Wahren et al, Int. J. Cancer 29:133-137 (1982).
Harlozinska et al, Eur. J. Surg. Oncol.17:59-64 (1991).
Reck et al, Tumor Biol.13:110-111 (1992).
Radosevich et al., Tumor Biol., vol. 10, pp. 281-288, 1989.
Barnett et al., Genomics , vol. 3, pp. 59-66, 1988.
Suzuki et al., Cancer Res., vol. 47, No. 18, pp. 4782-4787, 1987 (abstract only).
Allard William J.
Barnett Thomas R.
Elting James J.
Bayer Corporation
Eyler Yvonne
Klawitter Andrew L.
Scheiner Toni R.
LandOfFree
Monitoring of NC 50/90 in blood samples of breast cancer patient does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Monitoring of NC 50/90 in blood samples of breast cancer patient, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monitoring of NC 50/90 in blood samples of breast cancer patient will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1387333