Chemistry: physical processes – Physical processes – Crystallization
Patent
1980-11-17
1983-02-01
Chin, Peter
Chemistry: physical processes
Physical processes
Crystallization
422 56, 422 57, 422 61, G01N 3350
Patent
active
043713742
ABSTRACT:
A method of monitoring metabolic control in a diabetes patient comprising measuring the amount of non-enzymatic glycosylated amino acids and peptides in urine of the patient; a method of measurement and a test kit for the measurement are disclosed.
REFERENCES:
patent: 4235601 (1980-11-01), Deutsch et al.
patent: 4269605 (1981-05-01), Dean et al.
Bisbee et al., A Method for Measuring Hydroxylysine and Glycosylated Hydroxylysines in Urine and Protein Hydrolysates, Clinica Chimica Acta, 90, (1978), 29-36.
R. J. Koenig and A. Cerami: "Synthesis of Hemaglobin A.sub.1.sbsb.c in Normal and Diabetic Mice: Potential Model of Basement Membrane Thickening: Proc. Nat. Acad. Sci. 72 at 3,687-3,691, (1975).
F. J. Stevens, H. Vlassara, A. Abati, and A. Cerami: "Non-Enzymatic Glycosylation of Hemoglobin", J. Biol. Chem. 252 at 2,998-3,002, (1977).
V. M. Monnier and A. Cerami: "Nonenzymatic Browning in Vivo: Possible Aging Process of Long-Lived Proteins", Science 211 at 491-493, (1981).
M. Brownlee, H. Vlassara, and A. Cerami: "Measurement of Glycosylated Amino Acids and Peptides from Urine of Diabetic Patients Using Affinity Chromatography", Diabetes 29 at 1,004-1,047, (1980).
R. J. Koenig, V. J. Stevens, and A. Cerami: "Non-Enzymatic Glycosylation and Browning of Hemoglobin and Other Body Proteins", J. Applied Biochem. 2 at 431-438, (1980).
CLINISTIX.RTM. Reagent Strips for Urinalysis, Ames Division, Miles Laboratories, Inc., 1979, (Revised 5/81).
CLINITEST.RTM. 2-Drop Method for the Quantitative Determination of Reducing Sugars in Urine, Ames Division, Miles Laboratories, Inc., 1979, (Revised 4/81).
CLINITEST.RTM. 2-Drop Method using Ames CLINITEST Reagent Tablets for the Quantitative Determination of Reducing Sugars in Urine, Ames Division, Miles Laboratories, Inc., 1979, (Revised 11/80).
Brownlee Michael
Cerami Anthony
Vlassara Helen
Chin Peter
The Rockefeller University
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