Monitoring ethylene oxide sterilization residual with enzymes

Details Monitoring ethylene oxide sterilization residual with enzymes Monitoring ethylene oxide sterilization residual with enzymes

1977-05-17

1979-07-31

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

23232R, 435 21, 435 28, 435 31, C12K 100, G01N 3114

Patent

active

041629426

ABSTRACT:
A method for indicating possible biological hazard due to sterilization residual, e.g. ethylene oxide sterilization residual, involves extracting residual, contacting extracted residual with enzyme, and providing an indication of enzyme deactivation.

REFERENCES:
patent: 3597235 (1971-08-01), Kramer
patent: 3738811 (1973-06-01), Cheng
patent: 3852034 (1974-12-01), Gunther
Gunther, "Safety of Ethylene Oxide Gas Residuals part i", American Journal of Hospital Pharmacy, vol. 31, pp. 558-561 (1974).
Gunther, "Safety of Ethylene Oxide Gas Residuals Part ii", American Journal of Hospital Pharmacy, vol. 31, pp. 684-686 (1974).
Libicky, "Effect of Ethylene Oxide Sterilization on the Activity of some Organ Preparations. II Effect of Ethylene Oxide on Crystalline Pancreatic Enzymes High Pressure Sterilization", Chem. Abstracts, vol. 67, No. 25, pp. 10739-10740 (1967), Abs. #114012u.

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