Monitoring blood flow in the retina using a line-scanning...

Optics: eye examining – vision testing and correcting – Eye examining or testing instrument – Objective type

Reexamination Certificate

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Reexamination Certificate

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07404640

ABSTRACT:
Real time, high-speed image stabilization with a retinal tracking scanning laser ophthalmoscope (TSLO) enables new approaches to established diagnostics. Large frequency range (DC to 19 kHz), wide-field (40-deg) stabilized Doppler flowmetry imaging is described for human subjects. The fundus imaging method is a quasi-confocal line-scanning laser ophthalmoscope (LSLO). The retinal tracking system uses a confocal reflectometer with a closed loop optical servo system to lock onto features in the ocular fundus and automatically re-lock after blinks. By performing a slow scan with the laser line imager, frequency-resolved retinal perfusion and vascular flow images can be obtained free of eye motion artifacts.

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Kobayashi et al., “Confocal scanning laser ophthalmoscope with a slit aperature,” J. Phys. Sci. Technol. 2, 287-292 (1991).
Heacock et al., “Imaging of the choroid with the scanning slit laser ophthalmoscope (SSLO),” SPIE vol. 3591, 456-464 (1999).
Hammer et al., “Compact scanning laser ophthalmoscope with high-speed retinal tracker,” vol. 42, No. 22, 4621-4632 (2003).

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