Image analysis – Applications – Biomedical applications
Reexamination Certificate
2005-09-06
2005-09-06
Dastouri, Mehrdad (Department: 2623)
Image analysis
Applications
Biomedical applications
C382S170000, C436S050000, C356S317000
Reexamination Certificate
active
06941005
ABSTRACT:
Methods, systems and apparatus are provided for sorting particles in a stream of a sample in a flow cytometer by producing from a stable sort having desirable sort characteristics multiple images of a portion of the stream; generating from the multiple images an averaged numerical reference standard representative of the stable sort; continuously collecting during the sorting multiple running images of the portion of the stream; generating from the multiple running images at least one numerical sample average representative of the sample sort of each collection of the multiple running images; and comparing each numerical sample average to the numerical reference standard and determining whether a sample average exhibits a deviation from the reference standard that requires an adjustment of the sort. The sort may then be adjusted to eliminate or reduce the deviation and maintain the stable sort of the reference histogram. A novel imaging apparatus may be employed in a flow cytometer performing this method.
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Burr Robert C.
Lary Todd P.
Riley John S.
Snow Christopher W.
Alter Mitchell E.
Coulter International Corp.
Dastouri Mehrdad
Howson and Howson
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