Monitoring an immune response by analysis of amplified immunoglo

Details Monitoring an immune response by analysis of amplified immunoglo Monitoring an immune response by analysis of amplified immunoglo

1994-04-19

1998-11-17

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, C12Q 168, C12P 1934

Patent

active

058374477

ABSTRACT:
An approach to monitoring immune responses relies on determining the range of sizes of amplified DNAs which code for the CDR3 regions of Ig or TcR molecules of one or more classes or families. Typically the relative quantity of DNAs corresponding to different CDR3 regions of the Ig or TcR molecules of a class is also determined. The progress of an immune response is followed by making these determinations at different times.

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