Molluscan ligament polypeptides and genes encoding them

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435 691, 4353201, 435325, 536 231, 536 235, C12N 120, C12N 1500, C12P 2106, C07H 2102

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061271667

ABSTRACT:
The invention provides substantially pure abductin protein and polypeptides, polypeptides composed of multiple repeats of the glycine-rich repeat sequences of abductin, and hybrid polypeptides containing an abductin polypeptide linked to another protein or polypeptide, e.g., an elastin or fibroin (silk) polypeptide, as well as nucleic acids encoding these polypeptides. The abductin polypeptides and their derivatives can be used in the manufacture of a broad range of biomaterials ranging from light-weight durable fabric for clothing to matrices useful for human tissue and organ prostheses.

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