Molecules with antibody combining sites that induce asymmetry

Details Molecules with antibody combining sites that induce asymmetry Molecules with antibody combining sites that induce asymmetry

1991-10-22

1993-10-05

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

4351885, 435197, 43524027, 5303889, C12P 742, C12N 900

Patent

active

052504263

ABSTRACT:
Monoclonal antibodies or paratope-containing portions thereof are disclosed that immunoreact with an enol ester substrate ligand having a prochiral center and catalytically hydrolyze a single predetermined e

REFERENCES:
patent: 4342566 (1980-02-01), Theofilopoulos et al.
patent: 4361549 (1982-11-01), Kung et al.
patent: 4659567 (1987-04-01), Tramontano et al.
patent: 4792446 (1988-12-01), Kim et al.
patent: 4888281 (1989-12-01), Schochetmann et al.
patent: 5030717 (1991-07-01), Tramontano et al.
patent: 5156965 (1992-10-01), Schochetman et al.
Blackburn, G. M., et al., (1989), Biochem. J., 262, 381-390.
Lerner, R. A., et al., (1988), Bioassays, 9, 107-112.
Pollack, S. J., et al., (1989), J. Am. Chem. Soc., 111, 5961-5962.
Janda, K. D., et al., (1989), Science, 244, 437-440.
Slobin, Biochemistry, 5:2836-2844 (1966).
Kohnen et al., FEBS Letters, 100:137-140 (1979).
Kohnen et al., Biochim. Biophys. Acta, 629:328-337 (1980).
Kohnen et al., FEBS Letters, 111:427-431 (1980).
Jencks, W. P., Catalysis in Chemistry and Enzymology, pp. 287-289 (McGraw-Hill, New York, 1969).
Lerner, Tramontano and Janda, Science, 234, 1566 (1986).
Pollack, Jacobs and Schultz, Science, 234, 1570 (1986).
Leon et al., Biochem., 10, 1424 (1971).
Jacobs et al., J. Am. Chem. Soc., 109, 2174 (1987).
Benkovic et al., Proc. Natl. Acad. Sci. USA, 85:5355 (1988).
Jackson et al., J. Am. Chem. Soc., 110:4841 (1988).
Napper et al., Science, 237:1041 (1987).
Hilvert et al., Proc. Natl. Acad. Sci. USA, 85:4953 (1988).
Jencks, W. P., Adv. Enzymology, 43, 219 (1975).
Pauling, L., Amer. Scientist, 36, 51 (1948).
Leinhard, G., Science, 180, 149 (1973).
Wolfenden, R., Acc. Chem. Res., 5, 10 (1972).
Jencks, W. P., XVII International Solvay Conference, (Nov. 1983), 2190.
Kohler and Milstein, Nature, 256, 495 (1975).
Bartlett, et al., Biochemistry, 22, 4618 (1983).
W. P. Jencks, Catalysis in Chemistry and Enzymology, ch. 10, (McGraw-Hill, New York, 1969).
Westerik et al., J. Biol. Chem., 247, 8195 (1972).
R. C. Thompson, Biochemistry, 12, 47 (1973).
Imperali et al., Biochemistry, 25, 3760 (1986).
Weaver et al., J. Mol. Biol., 114, 119 (1977).
Jacobson et al., J. Am. Chem. Soc., 103, 654 (1981).
W. N. Lipscomb, Acc. Chem. Res., 15, 232 (1982).
Christianson et al., J. Am. Chem. Soc., 108, 545 (1986).
L. M. Sayre, J. Am. Chem. Soc., 108, 1632 (1986).
Liu et al., Biochem., 80, 690 (1979).
Niman et al., Proc. Natl. Acad. Sci. USA, 77, 4524 (1980).
Niman et al., Monoclonal Antibodies and T-Cell Products, Katz, D. M. ed., 23-51, CRC Press, Boca Raton, Fla. (1982).
Shulman et al., Nature, 276, 269 (1978).
Galfre et al., Nature, 277, 131 (1979).
Goding, "Production of Monoclonal Antibodies by Cell Fusion", in Antibody as a Tool, Marchalonis et al., eds., John Wiley & Sons Ltd., p. 273 (1982).
Engvall, E., Methods Enzymol., 70, 419 (1980).
Stedman et al., Biochem. J., 26:2056 (1932).
Alles et al., Biol. Chem., 133: 375 (1940).
Laemmli, V., Nature, 227: 680 (1970).
Neuberger et al., Nature, 312:604-608 (1984).
Ochi et al., Proc. Natl. Acad. Sci. USA, 80:6351-55 (1983).
Oi et al., Proc. Natl. Acad. Sci. USA, 80:825-29 (1983).
Wood et al., Nature, 314:446-9 (1985).
Janda et al., Tetrahedron, 47:2503-2506 (1991).

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