Molecules of the card-related protein family and uses thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C424S184100, C424S185100, C424S192100, C424S193100, C424S194100, C435S007100

Reexamination Certificate

active

06936690

ABSTRACT:
Novel CARD-14 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-14 proteins, the invention further provides CARD-14 fusion proteins, antigenic peptides and anti-CARD-14 antibodies. The invention also provides CARD-14 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CARD-14 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

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