Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-04-14
2000-08-08
Scheiner, Laurie
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 6, 4352523, 4352872, 4353201, 435810, 536 235, 4241851, 4242681, 4242721, A61K 39015
Patent
active
061000671
ABSTRACT:
The invention relates to a polypeptide characterized in that it contains at least one peptide sequence carrying one or several epitopes characteristic of a protein produced at the sporozoite stage and in the hepatocytes infected by P. falciparum, this sequence comprising a sequence of from 10 amino acids to the maximal number of amino acids of the following peptide chain sequence:
REFERENCES:
patent: 4584268 (1986-04-01), Ceriani et al.
patent: 4666845 (1987-05-01), Mattes et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4687734 (1987-08-01), Chester
patent: 4708930 (1987-11-01), Kortright et al.
patent: 4725538 (1988-02-01), Senger
patent: 5112749 (1992-05-01), Brey, III et al.
patent: 5188967 (1993-02-01), Louvard et al.
Guerin-Marchand et al., "A liver-stage-specific antigen of Plasmodium falciparum characterized by gene cloning", Nature 320:164-167 (1987).
Stahl et al., "Differential antibody screening of cloned Plasmodium falciparum sequences expressed in Escherichia coli: Procedure for isolation of defined antigens and analysis of human antisera", PNAS USA 81:2456-2460 (1984).
Herrington et al., "Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites", Nature 328:257-259 (1987).
Weber et al., "Primary structure of a Plasmodium falciparum malaria antigen located at the merozoite surface and within the parasitophorous vacuole", J. Biol. Chem. 263:11421-11425 (1988).
Sharma et al., "Diversity of circumsporozoite antigen genes from two strains of the malarial parasite Plasmodium knowlesi", Science 229:779-782 (1985).
Triglia et al., "The complete sequence of the gene for the knob-associated histidine-rich protein from Plasmodium falciparum", EMBO Jour. 6:1413-1419 (1987).
Lal et al., "Structure of the gene encoding the circumsporozoite protein of Plasmodium yoelii", J. Biol. Chem. 262:2937-2940 (1987).
Galinski et al., "The circumsporozoite gene of the Plasmodium cynomolgi complex", Cell 48:311-319 (1987).
Lubert Stryer, (ed). Biochemistry, W.H. Freeman & Co. (San Francisco, 1975) pp. 14, 15, 512.
Gordon Langsley, "Paludisme: Vers Un Vaccin Multivalent", Biofutur (+Supp) 70:23 (1988).
Druilhe et al., Biological Abstracts, vol. 78, Abstract No. 59971 (1984).
Szarfman et al., Biological Abstracts, vol. 86, Abstract No. 49103 (1988).
Robine et al., "Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells?", PNAS, 82:8488-8492 (1985).
Alberts, B., et al., Molecular Biology of the Cell, Garland Publishing, Inc., p. 591 (1983).
Coudrier, E., et al., "Expression of two structural markers of brushborder intestinal mucosa: villin and a membrane glycoprotein (140Kd), in a human colon carcinoma cell line HT 29"; Submicros. Cytol.; 16:159-160 (1984).
Drenckhahn, D., et al, "Evidence for the association of villin with core filaments and rootlets of intestinal epithelial microvilli," Cell and Tissue Research, 228:409-414 (1983).
Ausiello, D., et al., "Identification of actin-binding protein and villin in toad bladder epithelia," American Journal of Physiology, 246:F101-F104 (1984).
Matsudaira, P., et al., "A gelsolin-like Ca2+ dependent actin binding domain in villin," Nature, 315:248-250 (1985).
Glenney, J., et al., "Demonstration of at least two different actin-binding sites in villin, a calcium-regulated modulator of F-actin organization," Chemical Abstracts, vol. 95: No. 13 (Sep. 1981), p. 249, Abst. No. 110516s.
Matsudaira, P., et al., "Mapping the cystine residues and actin-binding regions of villin by using antisera to the amino and carboxyl termini of the molecule," PNAS, vol. 82, No. 20, pp. 6788-6792 (Oct. 1985).
Reggio, H., et al., "Membranes in Growth and Development," publ. Alan R. Liss, pp. 89-105 (1982).
Mishell et al., Chapter 13, "Selected Methods in Cellular Immunology," W.H. Freeman and Co., pp. 787-304 (1980).
Jones, P., Section 19.3, "Selected Methods in Cellular Immunology," Ed. B.B. Mishell et al., W.H. Freeman and Co., 1080, pp. 407-411, 439, 440.
Raybould, T., et al., "Bovine-murine hybridoma that secretes bovine monoclonal antibody of defined specificity," Am. J. Vet. Res., vol. 46, No. 2, pp. 426-427 (1985).
Raybould, T., et al., A porcine-murine hybridoma that secretes porcine monoclonal antibody of defined specificity, Am. J. Vet. Res., vol. 46, No. 8, pp. 1768-1769 (1985).
Oi et al., Chapter 17, Selected Methods in Cellular Immunol. Ed. B. B. Mishell and S. M. Shiiqi, Freeman and Co., p. 351-372 (1980).
Pringault et al., "A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture" The EMBO Journal, vol. 5, No. 12 (1986) pp. 3119-3124.
Bazari et al., "Villin sequence and peptide map identify six homologous domains," PNAS 85:4986-4990 (Jul. 1988).
Andre et al., "Severin, delsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains," The Journal of Biological Chemistry, vol. 263, No. 2, pp. 722-727 (Jan. 1988).
Arpin et al., "Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity," Journal of Cell Biology, 107:1759-1766 (Nov. 1988).
Bazari et al., Abstract of Paper Presented at the Twenty-Seventh Annual Meeting of the American Society for Cell Biology, vol. 105, p. 112a, No. 623 (Nov. 1987).
Rousseau-Merck et al., "Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1," Human Genetics 78:130-133 (1988).
Glenney et al., "Demonstration of at least two different actin-binding sites in villin, a calcium-regulated modulator of F-actin organization," The Journal of Biological Chemistry, vol. 256, No. 15, pp. 8156-8161 (1981).
Dudowet et al., J. Cell Biol., 105:359-369 (1987).
Nowinski et al., Science, 210:537-539 (1980).
Websters II New Riverside Univ. Dictionary, Riverside Publishing Co., p. 778 (1988).
European Search Report EP 86/400957.
French Search Report FR 85/06707.
French Search Report FR 85/16820.
International Search Report PCT/FR86/00150.
Druilhe Pierre
Guerin-Marchand Claudine
Institut Pasteur
Scheiner Laurie
LandOfFree
Molecules containing at least one peptide sequence carrying one does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Molecules containing at least one peptide sequence carrying one , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Molecules containing at least one peptide sequence carrying one will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1149084