Molecule transfer/delivery system

Details Molecule transfer/delivery system Molecule transfer/delivery system

2011-07-19

2011-07-19

Ketter, James S (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C435S287300

Reexamination Certificate

active

07981638

ABSTRACT:
A molecule transfer and delivery system includes a loading zone (50) for loading a targeted cargo molecule (30) on a carrier molecule (20) making use of a hybridization nature of nucleotides, and an unloading zone (40) for unloading the targeted cargo molecule from the carrier molecule making use of the strand exchange nature of the nucleotides. Towing nucleotide chains including the first single-stranded nucleotides (21) with the first length are bound to the carrier molecule, and the second single-stranded nucleotides (31) with the second length longer than the first length are bound to the targeted cargo molecule. The third single-stranded nucleotides (41) with the same length as the second single-stranded nucleotides are bound to the unloading zone.

REFERENCES:
patent: 2003/0235854 (2003-12-01), Chan et al.
patent: 2009/0035751 (2009-02-01), He et al.
patent: 103 38 657 (2005-03-01), None
patent: WO 2004/096831 (2004-11-01), None
Yong-Zhong Du, et al., “Motor protein nano-biomachine powered by self-supplying ATP”, Chem. Commun., XP-002431642, No. 16, 2005, pp. 2080-2082.
Henry Hess, et al., “Powering Nanodevices with Biomolecular Motors”, Chem. Eur. J., XP-001203432, vol. 10, No. 9, 2004, pp. 2110-2116.
Henry Hess, et al., “Molecular shuttles based on motor proteins: active transport in synthetic environments”, Reviews in Molecular Biotechnology, XP-002300012, vol. 82, No. 1, 2001, pp. 67-85.
Sujatha Ramachandran, et al., “Selective Loading of Kinesin-Powered Molecular Shuttles with Protein Cargo and its Application to Biosensing”, Small, XP-002431644, vol. 2, No. 3, 2006, pp. 330-334.
Yuichi Hiratsuka, et al., “Controlling the Direction of Kinesin-Driven Microtubule Movements along Microlithographic Tracks,” Biophysical Journal, vol, 81, Sep. 2001, pp. 1555-1561.
Henry Hess, et al., “Light-Controlled Molecular Shuttles Made from Motor Proteins Carrying Cargo on Engineered Surfaces,” Nano Letters, vol. 1, No. 5, 2001, pp. 235-239.
Kazuaki Kato, et al., “Mircotubule-Cyclodextrin Conjugate: Functionalization of Motile Filament with Molecular Inclusion Ability,” Bioscience, Biotechnology, and Biochemistry, vol. 69, No. 3, Mar. 2005, pp. 646-648.

Affiliated with

Also associated with

Rating

Molecule transfer/delivery system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Molecule transfer/delivery system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Molecule transfer/delivery system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2629121