Molecular toxicology modeling

Details Molecular toxicology modeling Molecular toxicology modeling

2002-05-22

2008-08-19

Smith, Carolyn L. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C435S006120, C700S030000, C702S022000, C707S793000

Reexamination Certificate

active

07415358

ABSTRACT:
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known renal toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.

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