Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1990-05-07
1993-03-23
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530326, 424 11, 424 2, 436545, 436546, C07K 708, C07K 710, A61K 4300, G01N 33533
Patent
active
051965100
ABSTRACT:
A system or method for identifying and/or designing novel peptides and polypeptides comprising an amino acid sequence which mimics the molecular recognition site of either (a) a macromolecule such as an immunoglobulin, an enzyme, a receptor protein, a lectin or other binding protein or (b) a small molecule or a small region of a large molecule which functions as a ligand and is recognized and binds specifically to a macromolecule is disclosed. Novel peptides and polypeptides as well as conjugates of the peptides and polypeptides are also disclosed. Applications for use of the peptides, polypeptides and conjugates in a wide range of fields such as biomedicine; biological control and pest regulation; agriculture; cosmetics; environmental control and waste management; chemistry; catalysis; nutrition and food industries; military uses; climate control, etc. are disclosed.
REFERENCES:
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4629783 (1986-12-01), Cosand
patent: 4683291 (1987-07-01), Zimmerman et al.
patent: 4741900 (1988-05-01), Alvarez et al.
patent: 4792525 (1988-12-01), Rusolahti et al.
patent: 4879237 (1989-11-01), Ruoslahti et al.
Neuberger et al., "Recombinant Antibodies Possessing Novel Effector Functions," Nature 312:604-608 (1984).
Journal of Biological Chemistry, 260, Oct. 1985, Gartner et al., pp. 11891-11894.
Proceedings National Academy Sciences USA, 76, Jan. 1979, Yoshida et al., pp. 486-490.
EMBO Journal, 6, Oct. 1987, Altaba et al., pp. 3065-3070.
Cell, 37, May 1984, Richards et al., pp. 263-272.
Bioessays, 8, No. 2, Feb./Mar. 1988, Verhoeyen et al., pp. 74-78.
Science, 239 Jan. 1988, Saiki et al., pp. 487-491.
Mazza et al., 1985, Ann. Inst. Pasteur. Immunol. 136D:259-269.
Williams et al., 1988, Proc. Nat'l Acad. Scil 85: 6488-92.
Goni et al., 1988, J. Immunol 135: 4073-79.
Taub et al., 1989, J. Biol. Chem. 264: 259-65.
Williams et al., 1989, Biotech. 7: 471-574.
Rodwell et al., 1989, Nature 342: 99-100.
Alvarez Vernon L.
McKearn Thomas J.
Radcliffe Robert D.
Rodwell John D.
Cytogen Corporation
Nucker Christine M.
Woodward M. P.
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