Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2006-12-19
2009-11-24
Lam, Ann Y (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
Reexamination Certificate
active
07622295
ABSTRACT:
Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of branched peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner. Additionally, peptides that adopt helical structures are synthesized on a substrate surface and arrays are created having one or more features containing peptides capable of forming helixes.
REFERENCES:
patent: 3767398 (1973-10-01), Morgan
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5405783 (1995-04-01), Pirrung et al.
patent: 6121048 (2000-09-01), Zaffaroni et al.
patent: 6239273 (2001-05-01), Pease et al.
patent: 6379895 (2002-04-01), Fodor et al.
patent: 6406844 (2002-06-01), Pirrung et al.
patent: 6416952 (2002-07-01), Pirrung et al.
patent: 6444111 (2002-09-01), Montgomery
patent: 6506558 (2003-01-01), Fodor et al.
patent: 6515039 (2003-02-01), Ulbricht et al.
patent: 6566495 (2003-05-01), Fodor et al.
patent: 6630308 (2003-10-01), Stryer et al.
patent: 6750963 (2004-06-01), Sampas
patent: 6770436 (2004-08-01), Beecher et al.
patent: 6819843 (2004-11-01), Braun et al.
patent: 6919181 (2005-07-01), Hargreaves
patent: 6919211 (2005-07-01), Fodor et al.
patent: 2002/0151473 (2002-10-01), Braisted et al.
patent: 2004/0198637 (2004-10-01), Schultz et al.
patent: 2005/0026202 (2005-02-01), Edman et al.
patent: 1288664 (2003-03-01), None
patent: 1384504 (2004-01-01), None
patent: WO-97/39151 (1997-10-01), None
patent: WO-00/33804 (2000-06-01), None
patent: WO-2006105037 (2006-10-01), None
PCT International Search Report (dated May 25, 2007), International Application No. PCT/US2006/047854—International Filing Date Dec. 15, 2006, (10 pages).
PCT International Search Report (dated Mar. 20, 2008), International Application No. PCT/US2007/022287—International Filing Date Oct. 18, 2007 [Atty. Ref. No. 42P23055PCT], (13 pages).
Fodor, Stephen P., et al., “Light-Directed, Spatially Addressable Parallel Chemical Synthesis”, Science vol. 251, US American Association for the Advancement of Science, Washington, DC, XP000486899, (Feb. 15, 1991), (pp. 767-773).
McGall, Glenn, et al., “Light-Directed Synthesis of High-Density Oligonucleotide Arrays Using Semiconductor Photoresists”, Proc. Natl. Acad. Sci. USA, vol. 93, Nov. 1996, Applied Physical Sciences, (pp. 13555-13560).
Jean Philippe Pellois, et al., “Individually Addressable Parallel Peptide Synthesis on Microchips”, Nature biotechnology, vol. 20, Sep. 2002 (pp. 922-926).
C. Grant Wilson, et al., “Approaches to the Design of Radiation-Sensitive Polymeric Imaging Systems with Improved Sensitivity and Resolution”, J. Electrochem. Soc.: Solid-State Science and Technology, vol. 133, No. 1, Jan. 1986 (pp. 181-187).
Masamitsu Shirai, et al., “Photoacid and Photobase Generations: Chemistry and Applications to Polymeric Materials”, Prog. Polym. Sci., vol. 21, 1996 (pp. 1-45).
James F. Cameron, et al., “Photogeneration of Organic Bases fromo-Nitrobenzyl-Derived Carbamates”, J. Am. Chem. Soc. 1991, vol. 113 (pp. 4303-4313).
James F. Cameron, et al., “Base Catalysis in Imaging Materials. 1. Design and Synthesis of Novel Light-Sensitive Urethanes as Photoprecursors of Amines”, J. Org. Chem. 1990, vol. 55 (pp. 5919-5922).
Jean M. J. Fréchet, “The Photogeneration of Acid and Base Within Polymer Coatings: Approaches to Polymer Curing and Imaging”, Pure & Appl. Chem., vol. 64, No. 9, 1992 (pp. 1239-1248).
U.S. Appl. No. 11/395,899, filed Mar. 30, 2006 entitled “Massively Parallel Synthesis of Proteinaceous Biomolecules”, Inventor(s): John J. Rajasekaran, et al.
U.S. Appl. No. 11/322,268, filed Dec. 29, 2005 entitled “Massively Parallel Synthesis of Biopoloymeric Arrays”, Inventor(s): John J. Rajasekaran, et al.
U.S. Appl. No. 11/585,413, filed Oct. 23, 2006 entitled “Solid-Phase Mediated Synthesis of Molecular Microarrays”, Inventor(s): Narayan Sundararajan, et al.
U.S. Appl. No. 11/529,573, filed Sep. 29, 2006 entitled “Method for High Throughput, High Volume Manufacturing of Biomolecule Micro Arrays”, Inventor(s): Narayan Sundararajan, et al.
U.S. Appl. No. 11/647,579, filed Dec. 29, 2006 entitled “Fluorogenic Peptide Substrate Arrays for Highly Multiplexed, Real-Time Monitoring of Kinase Activities”, Inventor(s): Gunjan Tiwari, et al.
U.S. Appl. No. 11/529,554, filed Sep. 29, 2006 entitled Aptamer biochip for Multiplexed Detection of Biomolecules, Inventor(s): David J. Lui, et al.
U.S. Appl. No. 11/646,600, filed Dec. 28, 2006 entitled “Quality Control Methods for the Manufacture of Polymer Arrays”, Inventor(s): Gordon Holt, et al.
U.S. Appl. No. 11/647,580, filed Dec. 29, 2006 entitled “Novel Strategy for Selective Regulation of Background Surface Property in Microarray Fabrication and Method to Eliminate Self Quencing in Micro Arrays”, Inventors(s): Edelmira Cabezas et al.
Hodge Julia A.
Lam Ann Y
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