Scanning-probe techniques or apparatus; applications of scanning – Particular type of scanning probe microscopy or microscope;... – Scanning near-field optical microscopy or apparatus...
Reexamination Certificate
2006-05-12
2010-10-26
Berman, Jack I (Department: 2881)
Scanning-probe techniques or apparatus; applications of scanning
Particular type of scanning probe microscopy or microscope;...
Scanning near-field optical microscopy or apparatus...
C850S021000, C850S030000, C356S364000, C356S367000, C356S369000, C356S497000, C356S479000, C356S491000, C977S953000
Reexamination Certificate
active
07823215
ABSTRACT:
The present invention relates to near-field scanning optical microscopy (NSOM) and near-field/far-field scanning microscopy methods, systems and devices that permit the imaging of biological samples, including biological samples or structures that are smaller than the wavelength of light. In one embodiment, the present invention permits the production of multi-spectral, polarimetric, near-field microscopy systems that can achieve a spatial resolution of less than 100 nanometers. In another embodiment, the present invention permits the production of a multifunctional, multi-spectral, polarimetric, near-field/far-field microscopy that can achieve enhanced sub-surface and in-depth imaging of biological samples. In still another embodiment, the present invention relates to the use of polar molecules as new optical contrast agents for imaging applications (e.g., cancer detection).
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Berman Jack I
Crimaldi Joseph J.
Roetzel & Andress
Sahu Meenakshi S
The University of Akron
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