Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2000-07-08
2010-02-16
Peng, Bo (Department: 1648)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S320100, C435S236000, C435S235100
Reexamination Certificate
active
07662939
ABSTRACT:
Recombinant enteroviruses for use as vaccines or vectors, which are modified in tropism or virulence, are disclosed. Also disclosed are DNA constructs comprising enterovirus-derived molecular determinants of tropism or virulence for use in targeting genes of interest to specific cells or tissues. The recombinant enteroviruses and DNA constructs comprise molecular determinants of tropism and virulence localized in specific domains of the 5′NTR of the enteroviral genome.
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Bradrick Shelton S.
Dunn James J.
Romero Jose R.
Board of Regents of the University of Nebraska
Dann Dorfman Herrell & Skillman
Netter, Jr. Robert C.
Peng Bo
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