Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-05-19
1998-05-19
Knode, Marian C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 435325, 536 235, C07H 2104, C12N 1563, C12N 1581, C12N 1585
Patent
active
057535213
ABSTRACT:
The subject invention provides an isolated nucleic acid molecule which comprises nucleic acid encoding a polypeptide which has the biological activity of a receptor for picornavirus. The subject invention also provides a method which includes the-use of expression vectors in a host vector system for inducing the production of a picornavirus receptor.
REFERENCES:
Adams, R.L.P., et al., The Biochemistry of the Nucleic Acids, 9th Ed.. pp. 488-497 (1981). (Exhibit B).
Colonno, R.J., et al., Evidence for Direct Involvement of the Rhinovirus Canyon is Receptor Binding, Proc. Natl. Acad. Sci. USA 85:5449-5453 (1988).
Green, H., The Gene for the Poliovirus Receptor, N. Engl. J. Med. 290: 1018-1019 (1974). (Exhibit C).
Hogan, et al., Manip. the Mouse Embryo, Cold Spring Harbor Lab, pp. 153-203 (1986).
Holland J., et al, The Mammalian Cell Virus Relationship, J. Exp. Med. 110:65-80 (1959).
Holland, J.J., Receptor Affinities as Major Determinants of Enterovirus Tissue Tropisms in Humans, Virology 15:312-326 (1961).
Tissue Tropisms in Humans, Virology 15:312-326 (1961).
Jubelt, B., et al., Pathogenesis of Human Poliovirus infection in Mice, J. Neuropath. Expt. Neurol. 39:138-148 (1980).
Kohara, M., et al., A Recombinant Virus between the Sabin 1 and Sabin 3 Vaccine Strains of Poliovirus as a Possible Candidate for a New Type 3 Poliovirus Live Vaccine Strain, J. Virol. 62:2828-2835 (1988).
Mapoles, J.E., et al., Purification of a HeLa Cell Receptor Protein for Group B Coxsackieviruses, J. Virol. 55(3):560-566 (1985). (Exhibit D).
Menedelsohn, C.L., et al., Cellular Receptor for Poliovirus: Molecular Cloning, Nucleotide Sequence, and Expression of a New Member of the Immunoglobulin Superfamily, Cell 56:855-856 (1989).
Mendelsohn, C., et al., Transformation of a Human Poliovirus Receptor Gene into Mouse Cells, Proc. Natl. Acad. Sci. USA 83:7845-7849 (1986).
Minor, P.D., et al. Monoclonal Antibodies which Block Cellular Receptors of Poliovirus, Virus Res. 1:203-212 (1984).
Nobis, P., et al., Production of a Monoclonal Antibody against an Eptiope on HeLa Cells that Is the Functional Poliovirus Binding Site, J. Gen Virol. 66:2563-2569 (1985).
Virol. 66:2563-2569 (1985).
Scangos, G. and Bieberich, C., Gene Transfer into Mice, Adv. in Genetics 24:285-322 (1987).
Seed, B., and Aruffo, A., Molecular Cloning of the CD2 Antigen, the T-cell Erythrocyte Receptor, by a Rapid Immunoselection Procedure, Proc. Natl Acad. Sci. 84:3365-3369 (1987).
Acad. Sci. 84:3365-3369 (1987).
Shepley, M.P., et al., Monoclonal Antibody Identification of a 100 kDa Membrane Protein in HeLa Cells and Human Spinal Cord Involved in Poliovirus Attachment, Proc. Natl. Acad. Sci. USA 85:7743-7747 (1988).
Suggs, S.V., et al., Use of Synthetic Oligonucleotides as Hybridization.
Probes: Isolation of Cloned cDNA Sequence for Human b2-Microglobin, Proc.
Natl. Acad. Sci. USA 78(11) :6613-6617 (1981). (Exhibit E).
Weis, W., et al. Structure of the Influenza Virus Haemagglutinin Complexed with Its Receptor, Sialic Acid, Nature 333:426-431 (1988).
Costantini Frank
Mendelsohn Cathy
Racaniello Vincent
Gucker Stephen
Knode Marian C.
The Trustees of Columbia University in the City of New York
White John P.
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