Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-08-16
1999-02-09
Myers, Carla J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 530300, 530350, 536 235, 536 2431, C07H 2104, C12N 121, C12N 1500, C07K 14435
Patent
active
058692886
ABSTRACT:
Four cockroach allergens are purified, described, characterized and sequenced. The nucleotide sequence responsible for expression of the allergen, and the amino acid sequence thereof, are set forth. These allergens induce IgE antibody binding, which may generate an allergic or asthmatic response in sensitive individuals. The allergens are expressed by one of the dominant cockroach strains in the United States, B. germanica. Sequence analysis allows classification of the allergens in major protein classifications.
REFERENCES:
Pollart et al. J. of Immunology 87: 511-521, 1991.
Chapman et al. J. Clinical Immunology 93: 205, 1994.
Arruda et al. International Archives of Allergy and Immunology 107: 295-297, 1995.
Arruda L. Karla
Chapman Martin
Myers Carla J.
The University of Virginia Patent Foundation
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