Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1991-05-13
1993-08-24
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
43525231, 4353201, 435 691, 435202, 435219, 435222, 435226, C12N 1503, C12N 121, C12N 1575, C12N 1563
Patent
active
052388336
ABSTRACT:
Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
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Andreoli Peter M.
Mulleners Leo J. S. M.
Sanders Johan P. M.
van den Berg Johannes A.
Van Ee Jan H.
Gist-brocades, NV
Rae-Venter Barbara
Schwartz Richard A.
Vogel Nancy T.
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